Adenosine deaminase, nitric oxide, superoxide dismutase, and xanthine oxidase in patients with major depression: Impact of antidepressant treatment

Herken, Hasan; Gurel, Ahmet; Selek, Salih; Armutcu, Ferah; Ozen, Murat; Bulut, Mahmut; Kap, Ozlem; Yumru, Mehmet; Savas, Haluk; Akyol, Omer

doi:10.1016/j.arcmed.2006.10.005

Adenosine deaminase, nitric oxide, superoxide dismutase, and xanthine oxidase in patients with major depression: Impact of antidepressant treatment

Herken H., Gurel A., Selek S., Armutcu F., Ozen M. E. , Bulut M., ...More

ARCHIVES OF MEDICAL RESEARCH, vol.38, no.2, pp.247-252, 2007 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 38 Issue: 2
Publication Date: 2007
Doi Number: 10.1016/j.arcmed.2006.10.005
Title of Journal : ARCHIVES OF MEDICAL RESEARCH
Page Numbers: pp.247-252

Abstract

Background. There has been much evidence in recent years that free oxygen radicals and nitric oxide (NO) may play an important role in the pathophysiology of neuropsychiatric disorders. In this study, we aimed to investigate whether NO, xanthine oxidase (XO), superoxide dismutase (SOD), and adenosine deaminase (ADA) levels are associated with major depression (MD) and to evaluate the impact of antidepressant treatments on NO, SOD, ADA and XO levels in MD.