Prevalence and clinical significance of a patent foramen ovate in patients with chronic obstructive pulmonary disease


Hacievliyagil S., Gunen H., Kosar F., Sahin I., Kilic T.

RESPIRATORY MEDICINE, cilt.100, ss.903-910, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 100 Konu: 5
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.rmed.2005.08.015
  • Dergi Adı: RESPIRATORY MEDICINE
  • Sayfa Sayıları: ss.903-910

Özet

Background: A patent foramen ovate (PFO) is not widely recognized as a factor contributing to hypoxemia in patients with chronic obstructive pulmonary disease (CCPD). We therefore sought to clarify the prevalence and clinical significance of a PFO in patients with COPD, and to analyze the factors related to its occurrence. Methods: This study included 52 consecutive stable patients with COPD and 50 healthy controls. The demographic and clinical features of the study group were noted. To test for a PFO, standard and contrast transthoracic echocardiographic examinations were performed while resting and during the Valsalva maneuver (VM). Patients performed 6-min walking tests (6 MWT), and the distances traveled were measured.