Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in Turkey

ONER, R; GUMRUK, F; Acar, CEREN; ONER, C; GURGEY, A; ALTAY, C

Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in Turkey

ONER R., GUMRUK F., Acar C., ONER C., GURGEY A., ALTAY C.

HAEMATOLOGICA, cilt.85, sa.3, ss.320-321, 2000 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Kısa Makale
Cilt numarası: 85 Sayı: 3
Basım Tarihi: 2000
Dergi Adı: HAEMATOLOGICA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.320-321
İnönü Üniversitesi Adresli: Hayır

Özet

Molecular pathology of glucose-6-phosphate dehydrogenase (G6PD) was studied in 50 unrelated red cell G6PD deficient Turkish males. DNA analysis of G6PD genes revealed that 40 of the 50 subjects (80%) had G6PD B- 563T, 2 subjects (4%) A- (376G/202A) and one subject (2%) G6PD Chatam (1003A). The remaining 7 subjects (14%) did not have any of these three mutations.