Determination of serum bile acids routinely may prevent delay in diagnosis of total parenteral nutrition-induced cholestasis

Demircan M., Ergun O., Avanoglu S., YILMAZ BARBET F., Ozok G.

JOURNAL OF PEDIATRIC SURGERY, cilt.34, sa.4, ss.565-567, 1999 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 4
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1016/s0022-3468(99)90074-x
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.565-567
  • İnönü Üniversitesi Adresli: Evet

Özet

Background/Porpose: Early diagnosis of development of cholestasis is a current major problem for patients receiving total parenteral nutrition (TPN). Conventional tests for hepatic function such as serum transaminases and alkaline phosphatase do not often reflect simultaneously histopathologic changes of the liver. The aim of this study is to find out the relationships between conventional hepatic function tests, total serum bile acid concentrations (TSBA), and the histopathologic changes in the liver during TPN administration in rats.