Antioxidant effects of N-acetylcysteine in a neonatal rat model of necrotizing enterocolitis

Creative Commons License

Ozdemir R., YURTTUTAN S., SARI F. N., UYSAL B., UNVERDI H. G., CANPOLAT F. E., ...Daha Fazla

JOURNAL OF PEDIATRIC SURGERY, cilt.47, sa.9, ss.1652-1657, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 9
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.jpedsurg.2012.02.016
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1652-1657
  • İnönü Üniversitesi Adresli: Evet

Özet

Background/Purpose: Hypoxia and ischemia appear to play an important role in the pathogenesis of necrotizing enterocolitis (NEC), which may be related to oxygen-derived free radical formation. This study was designed to evaluate the role of oxidative stress and potentially beneficial effects of N-acetylcysteine (NAC) in a neonatal rat model of NEC.