Study for the Diagnostic Screening of Paroxysmal Nocturnal Hemoglobinuria in Older Patients with Unexplained Anemia and/or Cytopenia


Ozdemir Z. N. , İLHAN O., Ozet G., Falay M., Yenerel M., Tuglular T., ...Daha Fazla

CLINICAL LABORATORY, cilt.66, ss.1709-1715, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 66 Konu: 9
  • Basım Tarihi: 2020
  • Doi Numarası: 10.7754/clin.lab.2020.191218
  • Dergi Adı: CLINICAL LABORATORY
  • Sayfa Sayıları: ss.1709-1715

Özet

Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematopoietic stem cell disease that may lead to weakness and death of patients, if unrecognized and untreated. Although consensus guidelines were reviewed recently for the diagnostic screening of PNH with multi-parameter flow cytometry (FCM), until now, no study has investigated the efficiency of such clinical indications in older patients.