Effects of early administration of dexamethasone, N-acetylcysteine and aprotinin on inflammatory and oxidant-antioxidant status after lung contusion in rats

TÜRÜT, HASAN; Ciralik, Harun; Kilinc, Metin; Ozbag, DAVUT; Imrek, Secil

doi:10.1016/j.injury.2008.05.001

Effects of early administration of dexamethasone, N-acetylcysteine and aprotinin on inflammatory and oxidant-antioxidant status after lung contusion in rats

Atıf İçin Kopyala

TÜRÜT H., Ciralik H., Kilinc M., Ozbag D., Imrek S. S.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, cilt.40, sa.5, ss.521-527, 2009 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 40 Sayı: 5
Basım Tarihi: 2009
Doi Numarası: 10.1016/j.injury.2008.05.001
Dergi Adı: INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.521-527
İnönü Üniversitesi Adresli: Hayır

Özet

Introduction: This experimental setting was undertaken to elucidate and confirm the role of inflammatory and oxidant-antioxidant mechanisms on blunt injury induced moderate pulmonary contusion (PC). We intended to determine the effects of dexamethasone (DXM), N-acetylcysteine (NAC) and aprotinin (APR) in terms of their ability to diminish the consequences of acute lung injury due to PC.