Microwave Assisted Suzuki-Miyaura and Ullmann Type Homocoupling Reactions of 2-and 3-Halopyridines Using a Pd(OAc)(2)/Benzimidazolium Salt and Base Catalyst System

Yilmaz U., Deniz S., KÜÇÜKBAY H., ŞİRECİ N.

MOLECULES, cilt.18, sa.4, ss.3712-3724, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 4
  • Basım Tarihi: 2013
  • Doi Numarası: 10.3390/molecules18043712
  • Dergi Adı: MOLECULES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3712-3724
  • Anahtar Kelimeler: Suzuki-Miyaura reaction, homocoupling, N-heterocyclic carbene, microwave, pyridine derivatives, CROSS-COUPLING REACTIONS, ARYL HALIDES, HECK-MIZOROKI, EFFICIENT CATALYST, PALLADIUM, COMPLEX, BIARYLS, CHLORIDES, BROMIDES, WATER
  • İnönü Üniversitesi Adresli: Evet

Özet

A number of novel benzimidazole derivatives 1-4 were synthesized and the catalytic activity of these compounds in a catalytic system consisting of a benzimidazolium salt/Pd(OAc)(2)/K2CO3 were investigated in the Suzuki-Miyaura and Ullmann type homocoupling reactions under microwave irradiation. We obtained both cross coupling and homocoupling products of pyridine and some side products such as dimethylaminopyridine and unsubstituted pyridine.