Evaluation of the Efficacy of Plasma Shower and 585 Nm Q-Switched Laser in the Treatment of Mild to Moderate Acne Vulgaris
Journal of Cosmetic Dermatology, cilt.25, sa.4, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 25 Sayı: 4
- Basım Tarihi: 2026
- Doi Numarası: 10.1111/jocd.70876
- Dergi Adı: Journal of Cosmetic Dermatology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Anahtar Kelimeler: 585 nm Q-switch laser, acne vulgaris, cold atmospheric plasma, laser therapy, plasma shower
- İnönü Üniversitesi Adresli: Evet
Özet
Objective: The aim of this study is to comparatively evaluate the clinical efficacy, safety profiles, and effects on different clinical components of plasma shower and 585 nm Q-Switch laser in the treatment of mild to moderate acne vulgaris. Materials and Methods: A total of 47 patients with mild to moderate acne vulgaris were prospectively enrolled and allocated to either plasma shower (n = 24) or 585 nm Q-Switch laser (n = 23) treatment groups. Acne severity was assessed using the Global Acne Grading System (GAGS) at three time points: Baseline, week 2, and week 4. Repeated measures ANOVA and independent samples t-test were used for statistical analysis. Results: An average improvement of 42.5% in GAGS scores was observed in the plasma shower group at the fourth week, while this rate was 32.2% in the 585 nm Q-Switch laser group. This difference between the two groups was statistically significant (p = 0.007). Clinical observations revealed that the plasma shower provided faster and more pronounced regression in inflammatory papules and pustules, while the 585 nm Q-Switch laser was more effective on post-inflammatory erythema. Both methods were found to be safe and well-tolerated by patients. Conclusion: Plasma shower appears to be more effective than the 585 nm Q-Switch laser in the treatment of mild to moderate acne vulgaris, particularly in reducing active inflammatory lesions. The 585 nm Q-Switch laser is a valuable treatment option for the removal of post-inflammatory erythema. Clinicians may choose between these modalities or develop combined protocols based on the predominant clinical component of acne.