A synthesis and properties of 1-substituted 1,4,5,6-tetrahydropyrimidines

Alici B., CETINKAYA E., CETINKAYA B.

HETEROCYCLES, cilt.45, sa.1, ss.29-36, 1997 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 1
  • Basım Tarihi: 1997
  • Dergi Adı: HETEROCYCLES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.29-36
  • İnönü Üniversitesi Adresli: Evet

Özet

The condensation of 1-substituted 1,3-diaminopropane with N,N-dimethylformamide dimethylacetal gives 1-alkyl- or aryl-1,4,5,6-tetrahydropyrimidines (2) and (3). Alkylation of the tetrahydropyrimidine derivatives with alkyl halides produces the 1,3-dialkyltetrahydropyrimidinium salts (4 and 5). The attempted dehydrogenation of 2 with sulfur leads to insertion of sulfur on the molecule.