Is paracetamol responsible for fatal acute liver failure in pediatric patients after hip dysplasia surgery?

Ceylan M. F., Baskiran A., Varol F. İ., Samdanci E., Karakaplan M., Ozkan A. S.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, cilt.24, sa.20, ss.10806-10811, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 20
  • Basım Tarihi: 2020
  • Doi Numarası: 10.26355/eurrev_202010_23441
  • Dergi Adı: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.10806-10811
  • Anahtar Kelimeler: Developmental dysplasia, Paracetamol toxicity, Encephalopathy, Histopathological evaluation, ACETAMINOPHEN, HEPATOTOXICITY, CHILDREN
  • İnönü Üniversitesi Adresli: Evet

Özet

OBJECTIVE: It is well known that local complications, such as avascular necrosis and arthrosis can develop after surgery for developmental dysplasia of the hip (DDH). Thus far, systemic complications that may develop in such cases have not been identified in the literature. This study is the first case series to evaluate acute liver failure (ALF) development after DDH surgery in pediatric patients.