Background and aim: In this study we present the complications and outcomes of PSC patients after liver transplantation in a predominantly LDLT center.
Materials and methods: Adult and pediatric patients who underwent liver transplantation for PSC between February 2008 and October 2020 were included in the study. The demographic characteristics, presence of co- existing diseases, indications for transplantation, type of transplantation, and immunosuppressive treatments used were rec- orded. Patient survival, survival times, cause of death, recurrences, rejection, and biliary com- plications were recorded.

Results: Thirty patients who underwent liver transplantation for PSC were included in the study. Twenty-seven patients (90 %) were living donor transplants. The 1-, 3-, and 5-year survival rates after transplan- tation were 75.9 %, 74.9 %, and 74.9 %, respectively. Biliary compli- cations occurred in 15 patients (50 %). All patients with biliary com- plications were successfully treated with endoscopic and percutaneous interventional treatments. Chronic rejection occurred in three patients (10 %) and acute rejection occurred in five patients (13.3 %). PSC re- currence developed in five patients (18.5 %).

Conclusion: Biliary complications are the most common complication after liver transplantation in patients with PSC in our center, where LDLT is used extensively and PSC patients are followed closely with respect to biliary complications after transplantation