Protective effects of dexpanthenol in an experimental model of necrotizing enterocolitis


KARADAĞ A., ÖZDEMİR R. , KURT A., PARLAKPINAR H. , POLAT A. , VARDI N. , ...Daha Fazla

JOURNAL OF PEDIATRIC SURGERY, cilt.50, ss.1119-1124, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 50 Konu: 7
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.jpedsurg.2014.10.053
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Sayfa Sayıları: ss.1119-1124

Özet

Background/purpose: In pathogenesis of necrotizing enterocolitis (NEC), both oxidative stress and inflammation are considerable risk factors. The study was designed to evaluate whether administration of dexpanthenol (Dxp) is able to attenuate intestinal injury through the antioxidant and antiinflammatory mechanisms in a neonatal rat model of NEC.