Effects of caffeic acid phenethyl ester and epidermal growth factor on the development of caustic esophageal stricture in rats

Koltuksuz, U; Mutus, HM; Kutlu, R; Ozyurt, H; Cetin, S; Karaman, A; Gurbuz, N; Akyol, O; Aydin, NE

doi:10.1053/jpsu.2001.27032

Effects of caffeic acid phenethyl ester and epidermal growth factor on the development of caustic esophageal stricture in rats

Atıf İçin Kopyala

Koltuksuz U., Mutus H., Kutlu R., Ozyurt H., Cetin S., Karaman A., ...Daha Fazla

JOURNAL OF PEDIATRIC SURGERY, cilt.36, sa.10, ss.1504-1509, 2001 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 36 Sayı: 10
Basım Tarihi: 2001
Doi Numarası: 10.1053/jpsu.2001.27032
Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1504-1509
İnönü Üniversitesi Adresli: Hayır

Özet

Background/Purpose: An experimental study was performed to modify the healing response in caustic esophageal burns to prevent stricture development. Two different agents with different modes of actions, caffeic acid phenethyl ester (CAPE) and epidermal growth factor (EGF), were studied. CAPE has antiinflammatory, immunomodulatory, antioxidant, and antimitotic properties. EGF has known properties in supporting wound healing and in protecting esophagus from injuries.