Brain MR spectroscopy findings in neonates with hypothyroidism born to mothers living in iodine-deficient areas

Akinci A., Sarac K., Gungor S., Mungan I., Aydin O.

AMERICAN JOURNAL OF NEURORADIOLOGY, cilt.27, sa.10, ss.2083-2087, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 10
  • Basım Tarihi: 2006
  • Dergi Adı: AMERICAN JOURNAL OF NEURORADIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2083-2087
  • İnönü Üniversitesi Adresli: Hayır

Özet

BACKGROUND AND PURPOSE: Iodine deficiency and hypothyroxinemia have a negative effect on the development of the central nervous system during fetal and early postnatal life. MR spectroscopy is a sensitive technique for detecting the changes of brain metabolites in various neurodevelopmental disorders. By using MR spectroscopy, we aimed to show the decrease in N-acetylaspartate (NAA) levels in neonates with hypothyroidism who were born in iodine-deficient areas and its normalization with early thyroxine therapy.