Evaluation of the cardiovascular effects of varenicline in rats.

Selcuk E. B., SUNGU M., PARLAKPINAR H., ERMİŞ N., TASLIDERE E., VARDI N., ...Daha Fazla

Drug design, development and therapy, cilt.9, ss.5705-17, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9
  • Basım Tarihi: 2015
  • Doi Numarası: 10.2147/dddt.s92268
  • Dergi Adı: Drug design, development and therapy
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.5705-17
  • Anahtar Kelimeler: varenicline, smoking, cardiovascular, rat, electrocardiogram, histopathological evaluation, RECEPTOR PARTIAL AGONIST, NICOTINIC ACETYLCHOLINE-RECEPTOR, SMOKING-CESSATION, DISCRIMINATIVE STIMULUS, CONTROLLED TRIAL, RISK, ALPHA-4-BETA-2, EVENTS, MYELOPEROXIDASE, ARRHYTHMIAS
  • İnönü Üniversitesi Adresli: Evet

Özet

Background: Cardiovascular disease is an important cause of morbidity and mortality among tobacco users. Varenicline is widely used worldwide to help smoking cessation, but some published studies have reported associated cardiovascular events.