Attenuation of ureteral obstruction-induced renal injury by polyenylphosphatidylcholine.

AKIN M., DEMİRBİLEK S., Ay S., Gurunluoglu K., Turkmen E., TAS E., ...Daha Fazla

International journal of urology : official journal of the Japanese Urological Association, cilt.14, sa.4, ss.350-6, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 4
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1111/j.1442-2042.2006.01717.x
  • Dergi Adı: International journal of urology : official journal of the Japanese Urological Association
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.350-6
  • Anahtar Kelimeler: alpha smooth muscle actin, nuclear factor kappa beta, polyenylphosphatidylcholine, transforming growth factor-beta1, unilateral ureteral obstruction, GROWTH-FACTOR-BETA, NF-KAPPA-B, POLYUNSATURATED PHOSPHATIDYLCHOLINE, OXIDATIVE STRESS, ALPHA-TOCOPHEROL, NEPHROPATHY, KIDNEY, RATS, DILINOLEOYLPHOSPHATIDYLCHOLINE, CONSEQUENCES
  • İnönü Üniversitesi Adresli: Evet

Özet

Background: The cytoprotective, antioxidant and antifibrotic effects of polyenylphosphatidylcholine (lecithin, PPC) have been demonstrated both experimentally and clinically. The present study investigated whether PPC treatment has any beneficial effect on renal injury in unilateral partial ureteral obstruction (UUO) in rats.