Pemphigus: Epidemiology and Pathogenesis


Karincaoglu Y.

TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY, cilt.42, ss.1-4, 2008 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 42
  • Basım Tarihi: 2008
  • Dergi Adı: TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY
  • Sayfa Sayıları: ss.1-4

Özet

Pemphigus, a group of bullous diseases affecting the oral mucosa and the skin, is caused by antibody-mediated autoimmune reaction to desmogleins (Dsg), desmosomal transmembrane glycoproteins, leading to acantholysis. Pemphigus has a worldwide distribution but the incidence in patients of Jewish origin is higher. The disease has a peak incidence of occurrence between the 4th and 6th decades.