Altered Expression of ADAMTSs and HAPLNs in Preeclamptic Placenta

Kandemir S. I., Taskin I., Pektanc G., Tekin M. A., Demircan K.

ERCIYES MEDICAL JOURNAL, cilt.40, sa.2, ss.87-92, 2018 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5152/etd.2018.0126
  • Dergi Adı: ERCIYES MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.87-92
  • İnönü Üniversitesi Adresli: Hayır

Özet

Objective: Preeclampsia (PE) is a pregnancy-specific complication defined by the new onset of hypertension and proteinuria during the second trimester of pregnancy. The pathogenesis of PE remains poorly understood. Revealing the key factors involved in placental dysfunction is critical for the understanding the pathogenesis of PE. The aim of this study was to determine the expression levels of ADAMTSs and their molecular partners, TIMP-3 and HAPLNs in the placental tissues of women with PE.