The effects of iron and zinc status on prognosis in pediatric Wilson's disease


Gungor S. , SELİMOĞLU M. A. , VAROL F. İ. , GÜNGÖR S. , ÜREMİŞ M. M.

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, cilt.55, ss.33-38, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 55
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.jtemb.2019.05.010
  • Dergi Adı: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
  • Sayfa Sayıları: ss.33-38

Özet

Objectives: Wilson's disease (WD) is a metabolic disorder leading to hepatic and extrahepatic copper deposition. Several studies have reported that besides copper (Cu), iron (Fe) and zinc (Zn) are also accumulated at varying levels in various tissues in WD. However, there is not an adequate number of studies investigating the effects of Fe and Zn status on WD presentation and prognosis. We aimed to evaluate serum levels of ferritin (SFr), copper (SCu), and zinc (SZn) in WD and determine their role in disease presentation and prognosis.