The effects of iron and zinc status on prognosis in pediatric Wilson's disease

Gungor, ŞÜKRÜ; SELİMOĞLU, MUKADDER; VAROL, FATMA; GÜNGÖR, SERDAL; ÜREMİŞ, MUHAMMED

doi:10.1016/j.jtemb.2019.05.010

The effects of iron and zinc status on prognosis in pediatric Wilson's disease

Atıf İçin Kopyala

Gungor S., SELİMOĞLU M. A., VAROL F. İ., GÜNGÖR S., ÜREMİŞ M. M.

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, cilt.55, ss.33-38, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 55
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.jtemb.2019.05.010
Dergi Adı: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.33-38
İnönü Üniversitesi Adresli: Evet

Özet

Objectives: Wilson's disease (WD) is a metabolic disorder leading to hepatic and extrahepatic copper deposition. Several studies have reported that besides copper (Cu), iron (Fe) and zinc (Zn) are also accumulated at varying levels in various tissues in WD. However, there is not an adequate number of studies investigating the effects of Fe and Zn status on WD presentation and prognosis. We aimed to evaluate serum levels of ferritin (SFr), copper (SCu), and zinc (SZn) in WD and determine their role in disease presentation and prognosis.