Could Endocan, a Marker of Inflammation and Endothelial Dysfunction, be a New Diagnostic Marker for Fibromyalgia?

MERTOĞLU C., Gunay M., Yerligok O.

CLINICAL LABORATORY, cilt.64, sa.3, ss.405-410, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.7754/clin.lab.2017.171024
  • Dergi Adı: CLINICAL LABORATORY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.405-410
  • Anahtar Kelimeler: Endocan [endothelial cell-specific molecule-1 (ESM-1)], fibromyalgia, inflammation, endothelial dysfunction, RHEUMATOLOGY 1990 CRITERIA, CYTOKINES, SERUM, CLASSIFICATION, DISEASE, ESM-1, IL-6
  • İnönü Üniversitesi Adresli: Hayır

Özet

Background: Although the pathophysiology of fibromyalgia has not yet been fully clarified, inflammation and endothelial dysfunction have been suggested to occur in patients with fibromyalgia. In recent years, endocan has been reported as an important biomarker for inflammation and endothelial dysfunction. In this study, we investigated this mechanism by measuring the serum endocan levels in fibromyalgia patients.