Evaluation of reproductive and renal toxicity of varenicline in male rats


OĞUZ F. , BEYTUR A. , TAŞLIDERE E. , PARLAKPINAR H. , Oguz H. K. , Polat A., ...Daha Fazla

IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, cilt.22, ss.1392-1399, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 22 Konu: 12
  • Basım Tarihi: 2019
  • Doi Numarası: 10.22038/ijbms.2019.13986
  • Dergi Adı: IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
  • Sayfa Sayıları: ss.1392-1399

Özet

Objective(s): Varenicline is a selective partial agonist for the nicotinic acetylcholine receptor a4b2 subtype, which is widely used to treat smoking addiction. However, there is still no data about its potential toxic effects on tissues. In this study, we aimed to determine the varenicline-induced toxicity on reproductive and renal tissues in rats.