Multiple Intestinal Atresia in Two Siblings Born of a Close Consanguineous Marriage: Case Report


UĞURALP S. , Karaman A., Savaci S.

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, cilt.31, ss.482-486, 2011 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 31 Konu: 2
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5336/medsci.2009-13118
  • Dergi Adı: TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
  • Sayfa Sayıları: ss.482-486

Özet

Hereditary multiple intestinal atresia is the rarest form of multiple intestinal atresia with a presumed autosomal recessive mode of inheritance. Two consecutive male siblings were admitted due to non-bilious vomiting. A plain radiograph of the abdomen revealed a single air bubble and expanded stomach in both siblings. Barium contrast study showed unused colon in the first sibling. In the second sibling, barium contrast study indicated rectal obstruction. On laparotomy, there were multiple gastrointestinal atresia in both of them. No chromosomal abnormality was observed with cytogenetic studies. The parents were first cousins. Here, we present two siblings with hereditary multiple intestinal atresia born of close consanguineous marriage, and discussed possible etiopathogenesis.