Antiinflammatory and antioxidant activities of Trifolium resupinatum var. microcephalum extracts

Sabudak T., Dokmeci D., Ozyigit F., Isik E., Aydogdu N.

ASIAN JOURNAL OF CHEMISTRY, vol.20, no.2, pp.1491-1496, 2008 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 2
  • Publication Date: 2008
  • Journal Name: ASIAN JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1491-1496
  • Inonu University Affiliated: No

Abstract

The antiinflammatory and antioxidant activities of the ethanol extract of Ttifolium resupinatum L. var. microcephalum (Leguminosae) have been assessed on arthritic rats. The extract (1.35 and 13.5 mg/kg, i.p.) significantly reduced the paw edema induced by the complete Freund's adjuvant. Furthermore, it also inhibited lipid peroxidation. These effects of T resupinatum extract may be directly linked to the content in triterpene saponins and flavonoid compounds and consequently to their free radical scavenging activities.