Antiinflammatory and antioxidant activities of Trifolium resupinatum var. microcephalum extracts


Sabudak T., Dokmeci D., Ozyigit F., Isik E., Aydogdu N.

ASIAN JOURNAL OF CHEMISTRY, cilt.20, ss.1491-1496, 2008 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 20 Konu: 2
  • Basım Tarihi: 2008
  • Dergi Adı: ASIAN JOURNAL OF CHEMISTRY
  • Sayfa Sayıları: ss.1491-1496

Özet

The antiinflammatory and antioxidant activities of the ethanol extract of Ttifolium resupinatum L. var. microcephalum (Leguminosae) have been assessed on arthritic rats. The extract (1.35 and 13.5 mg/kg, i.p.) significantly reduced the paw edema induced by the complete Freund's adjuvant. Furthermore, it also inhibited lipid peroxidation. These effects of T resupinatum extract may be directly linked to the content in triterpene saponins and flavonoid compounds and consequently to their free radical scavenging activities.