The effects of dexmedetomidine on liver ischemia-reperfusion injury in rats

SAHIN, Taylan; BEGEÇ, ZEKİNE; TOPRAK, HÜSEYİN; POLAT, ALAADİN; VARDI, NİGAR; YÜCEL, AYTAÇ; DURMUŞ, MAHMUT; ERSOY, MEHMET

doi:10.1016/j.jss.2012.11.034

The effects of dexmedetomidine on liver ischemia-reperfusion injury in rats

SAHIN T., BEGEÇ Z., TOPRAK H. İ., POLAT A., VARDI N., YÜCEL A., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.183, sa.1, ss.385-390, 2013 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 183 Sayı: 1
Basım Tarihi: 2013
Doi Numarası: 10.1016/j.jss.2012.11.034
Dergi Adı: JOURNAL OF SURGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.385-390
İnönü Üniversitesi Adresli: Evet

Özet

Background: Ischemia-reperfusion (IR) injury of the liver may cause various types of damage to hepatic tissues. It can affect the prognosis of patients and the success of an operation. Dexmedetomidine is a selective alpha(2) receptor agonist. We investigated whether dexmedetomidine provides protection against IR-induced liver injury in rats.