The effects of dexmedetomidine on liver ischemia-reperfusion injury in rats


SAHIN T., BEGEÇ Z., TOPRAK H. İ., POLAT A., VARDI N., YÜCEL A., ...More

JOURNAL OF SURGICAL RESEARCH, vol.183, no.1, pp.385-390, 2013 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 183 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.1016/j.jss.2012.11.034
  • Journal Name: JOURNAL OF SURGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.385-390
  • Inonu University Affiliated: Yes

Abstract

Background: Ischemia-reperfusion (IR) injury of the liver may cause various types of damage to hepatic tissues. It can affect the prognosis of patients and the success of an operation. Dexmedetomidine is a selective alpha(2) receptor agonist. We investigated whether dexmedetomidine provides protection against IR-induced liver injury in rats.