The role of fecal calprotectin and lactoferrin in the diagnosis of necrotizing enterocolitis

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SELİMOĞLU M. A., Temel I., Yildirim C., Ozyalin F., Aktas M., Karabiber H.

PEDIATRIC CRITICAL CARE MEDICINE, vol.13, no.4, pp.452-454, 2012 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 13 Issue: 4
• Publication Date: 2012
• Doi Number: 10.1097/pcc.0b013e3182388ae9
• Journal Name: PEDIATRIC CRITICAL CARE MEDICINE
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.452-454
• Inonu University Affiliated: Yes

Abstract

Background: Early detection of necrotizing enterocolitis can improve the prognosis, however, there is not a reliable laboratory test to detect either newborns at risk for necrotizing enterocolitis development or those at early stages of the disease. Since fecal lactoferrin and fecal calprotectin are inflammatory markers of gastrointestinal diseases, it was hypothesized that both these biomarkers could be successfully used in the diagnosis of necrotizing enterocolitis.