The role of fecal calprotectin and lactoferrin in the diagnosis of necrotizing enterocolitis


SELİMOĞLU M. A. , Temel I., Yildirim C., Ozyalin F., Aktas M., Karabiber H.

PEDIATRIC CRITICAL CARE MEDICINE, cilt.13, ss.452-454, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 13 Konu: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1097/pcc.0b013e3182388ae9
  • Dergi Adı: PEDIATRIC CRITICAL CARE MEDICINE
  • Sayfa Sayıları: ss.452-454

Özet

Background: Early detection of necrotizing enterocolitis can improve the prognosis, however, there is not a reliable laboratory test to detect either newborns at risk for necrotizing enterocolitis development or those at early stages of the disease. Since fecal lactoferrin and fecal calprotectin are inflammatory markers of gastrointestinal diseases, it was hypothesized that both these biomarkers could be successfully used in the diagnosis of necrotizing enterocolitis.