The role of fecal calprotectin and lactoferrin in the diagnosis of necrotizing enterocolitis

SELİMOĞLU M. A., Temel I., Yildirim C., Ozyalin F., Aktas M., Karabiber H.

PEDIATRIC CRITICAL CARE MEDICINE, cilt.13, sa.4, ss.452-454, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1097/pcc.0b013e3182388ae9
  • Dergi Adı: PEDIATRIC CRITICAL CARE MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.452-454
  • İnönü Üniversitesi Adresli: Evet

Özet

Background: Early detection of necrotizing enterocolitis can improve the prognosis, however, there is not a reliable laboratory test to detect either newborns at risk for necrotizing enterocolitis development or those at early stages of the disease. Since fecal lactoferrin and fecal calprotectin are inflammatory markers of gastrointestinal diseases, it was hypothesized that both these biomarkers could be successfully used in the diagnosis of necrotizing enterocolitis.