The Effect of Caffeic Acid Phenethyl Ester (CAPE) Against Cholestatic Liver Injury in Rats

Coban, Sacid; Yildiz, Fahrettin; Terzi, Alpaslan; AL, BEHÇET; ÖZGÖR, DİNÇER; ARA, CENGİZ; Polat, Alaattin; Esrefoglu, Mukaddes

doi:10.1016/j.jss.2008.10.023

The Effect of Caffeic Acid Phenethyl Ester (CAPE) Against Cholestatic Liver Injury in Rats

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Coban S., Yildiz F., Terzi A., AL B., ÖZGÖR D., ARA C., ...More

JOURNAL OF SURGICAL RESEARCH, vol.159, no.2, pp.674-679, 2010 (SCI-Expanded)

Publication Type: Article / Article
Volume: 159 Issue: 2
Publication Date: 2010
Doi Number: 10.1016/j.jss.2008.10.023
Journal Name: JOURNAL OF SURGICAL RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.674-679
Inonu University Affiliated: Yes

Abstract

Objectives. Caffeic acid phenethyl ester (CAPE) has been subjected to considerable investigations that have revealed its antioxidant and anti-inflammatory activities in different conditions. But there is not a previous investigation about its effect on cholestatic liver injury. The aim of this study was to investigate the effect of CAPE in rat liver against cholestatic liver injury induced by bile duct ligation.