The association between vitamin D receptor polymorphisms and multiple sclerosis in a Turkish population

KAMIŞLI Ö., ACAR C., SÖZEN M. M., TECELLİOĞLU M., Yucel F. E., Vaizoglu D., ...Daha Fazla

MULTIPLE SCLEROSIS AND RELATED DISORDERS, cilt.20, ss.78-81, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.msard.2018.01.002
  • Dergi Adı: MULTIPLE SCLEROSIS AND RELATED DISORDERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.78-81
  • Anahtar Kelimeler: Multiple sclerosis, Vitamin D, Vitamin D receptor, Polymorphism, GENE POLYMORPHISMS, RISK, METAANALYSIS, AUTOIMMUNITY, JAPANESE, DISEASE
  • İnönü Üniversitesi Adresli: Evet

Özet

Background: Multiple sclerosis (MS) is a chronic, demyelinating disease of the central nervous system (CNS). Genetic and environmental factors are important in disease development. Many studies have investigated the relationship between MS and VDR polymorphisms. VDR gene polymorphism has not been previously studied in Turkish MS patients. We aimed to investigate the relationship between MS and VDR genotypes Taq I, Apa I and Fok I polymorphisms in a Turkish population.