Synthesis and cytotoxicity studies on new pyrazole-containing oxime ester derivatives
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, cilt.18, sa.6, ss.1315-1322, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 18 Sayı: 6
- Basım Tarihi: 2019
- Doi Numarası: 10.4314/tjpr.v18i6.24
- Dergi Adı: TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1315-1322
- Anahtar Kelimeler: Cytotoxic activity, E/Z isomer, Neuroblastoma cell, Oxime ester, Pyrazole, ANTICANCER ACTIVITY, DRUG DISCOVERY, ANTICONVULSANT, SOLUBILITY, IMIDAZOLE, A549
- İnönü Üniversitesi Adresli: Evet
Özet
Purpose: To synthesize a series of new 1-(2-naphthyl)-2-(1H-pyrazol-1-yl)ethanone oxime ester derivatives (5-12) with potential anticancer properties, and to determine their cytotoxic effects in mouse fibroblast and human neuroblastoma cell lines.