Synthesis and cytotoxicity studies on new pyrazole-containing oxime ester derivatives


KARAKURT A. , Bozbey I., USLU H. , SARI S., ÖZDEMİR Z. , ŞALVA E.

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, cilt.18, ss.1315-1322, 2019 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 18 Konu: 6
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4314/tjpr.v18i6.24
  • Dergi Adı: TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
  • Sayfa Sayıları: ss.1315-1322

Özet

Purpose: To synthesize a series of new 1-(2-naphthyl)-2-(1H-pyrazol-1-yl)ethanone oxime ester derivatives (5-12) with potential anticancer properties, and to determine their cytotoxic effects in mouse fibroblast and human neuroblastoma cell lines.