Synthesis, antimicrobial properties, and theoretical analysis of benzimidazole-2-ylidene silver(I) complexes

DEMİR DÜŞÜNCELİ S., Ayaz D., ÜSTÜN E., GÜNAL S., ÖZDEMİR N., DİNÇER M., ...Daha Fazla

JOURNAL OF COORDINATION CHEMISTRY, cilt.73, sa.13, ss.1967-1986, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 73 Sayı: 13
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1080/00958972.2020.1812587
  • Dergi Adı: JOURNAL OF COORDINATION CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chimica, Metadex
  • Sayfa Sayıları: ss.1967-1986
  • Anahtar Kelimeler: Antimicrobial activity, benzimidazolium salts, N-heterocyclic carbene, silver NHC complexes, HETEROCYCLIC CARBENE COMPLEXES, CRYSTAL-STRUCTURES, STRUCTURAL-CHARACTERIZATION, REACTIVITY DESCRIPTORS, BIOLOGICAL-ACTIVITY, AG(I) COMPLEXES, METAL-COMPLEXES, IN-VITRO, LIGANDS, POLYMER
  • İnönü Üniversitesi Adresli: Evet

Özet

A series of symmetrical and nonsymmetricalN,N-disubstituted benzimidazolium salts were synthesized asN-heterocyclic carbene precursors. These salts were treated with Ag2O to afford their corresponding mononuclear Ag(I)-NHC complexes. These compounds were characterized by spectroscopy techniques and analyzed by DFT/TDDFT and docking methods. Also, the structures of2aand2ewere determined by single-crystal X-ray crystallography. These new Ag-NHC complexes were screened for their antibacterial activities against Gram-positive, Gram-negative bacteria, fungi, and nosocomial agents.