Paraoxonase-1 gene in patients with chronic obstructive pulmonary disease investigation Q192R and L55M polymorphisms

GÜRBÜZ Ş., Yildiz M., KARA M., KARGÜN K., GÜRGER M., ATEŞÇELİK M., ...Daha Fazla

WORLD JOURNAL OF EMERGENCY MEDICINE, cilt.6, sa.3, ss.201-206, 2015 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5847/wjem.j.1920-8642.2015.03.007
  • Dergi Adı: WORLD JOURNAL OF EMERGENCY MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.201-206
  • İnönü Üniversitesi Adresli: Evet

Özet

BACKGROUND: The effect of increased oxidative stress on the development of chronic obstructive pulmonary disease (COPD) is well known. One of the antioxidative systems against oxidative stress in human body is paraoxonase (PON) enzyme that protects low density lipoproteins (LDL) against oxidation. This study aimed to explore the polymorphisms on PON1, Q192R, L55M genes of patients with COPD.