Paraoxonase-1 gene in patients with chronic obstructive pulmonary disease investigation Q192R and L55M polymorphisms


GÜRBÜZ Ş. , Yildiz M., KARA M., KARGÜN K., GÜRGER M., ATEŞÇELİK M., ...Daha Fazla

WORLD JOURNAL OF EMERGENCY MEDICINE, cilt.6, ss.201-206, 2015 (ESCI İndekslerine Giren Dergi) identifier identifier

Özet

BACKGROUND: The effect of increased oxidative stress on the development of chronic obstructive pulmonary disease (COPD) is well known. One of the antioxidative systems against oxidative stress in human body is paraoxonase (PON) enzyme that protects low density lipoproteins (LDL) against oxidation. This study aimed to explore the polymorphisms on PON1, Q192R, L55M genes of patients with COPD.