Prospective Follow-up of Children with Idiopathic Growth Hormone Deficiency After Termination of Growth Hormone Treatment: Is There Really Need for Treatment at Transition to Adulthood?


Camtosun E., Siklar Z., Berberoglu M.

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, vol.10, no.3, pp.247-255, 2018 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.4274/jcrpe.0010
  • Journal Name: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.247-255
  • Keywords: Growth hormone deficiency, transition, childhood, BONE-MINERAL DENSITY, GH-DEFICIENT, CHILDHOOD-ONSET, FINAL HEIGHT, BODY-COMPOSITION, ADOLESCENTS, DISCONTINUATION, CONTINUATION, THERAPY, TRIAL

Abstract

Objective: Continuation of growth hormone (GH) treatment in adolescents with severe childhood onset idiopathic GH deficiency (IGHD) during the transition period, irrespective of achievement of final height, is still debatable. We aimed to prospectively investigate the metabolic profile, bone mineral density (BMD) and body composition of patients with IGHD in whom GH treatments were terminated after they had reached their final height, six months after the cessation of therapy.