Prospective Follow-up of Children with Idiopathic Growth Hormone Deficiency After Termination of Growth Hormone Treatment: Is There Really Need for Treatment at Transition to Adulthood?

Camtosun E., Siklar Z., Berberoglu M.

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, cilt.10, sa.3, ss.247-255, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.4274/jcrpe.0010
  • Dergi Adı: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.247-255
  • Anahtar Kelimeler: Growth hormone deficiency, transition, childhood, BONE-MINERAL DENSITY, GH-DEFICIENT, CHILDHOOD-ONSET, FINAL HEIGHT, BODY-COMPOSITION, ADOLESCENTS, DISCONTINUATION, CONTINUATION, THERAPY, TRIAL
  • İnönü Üniversitesi Adresli: Evet

Özet

Objective: Continuation of growth hormone (GH) treatment in adolescents with severe childhood onset idiopathic GH deficiency (IGHD) during the transition period, irrespective of achievement of final height, is still debatable. We aimed to prospectively investigate the metabolic profile, bone mineral density (BMD) and body composition of patients with IGHD in whom GH treatments were terminated after they had reached their final height, six months after the cessation of therapy.