Protective Effect of Quercetin Against Oxidative Stressinduced Toxicity Associated With Doxorubicin and Cyclophosphamide in Rat Kidney and Liver Tissue


KOCAHAN S., DOĞAN Z., Erdemli E. , TAŞKIN E.

IRANIAN JOURNAL OF KIDNEY DISEASES, cilt.11, ss.124-131, 2017 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 11 Konu: 2
  • Basım Tarihi: 2017
  • Dergi Adı: IRANIAN JOURNAL OF KIDNEY DISEASES
  • Sayfa Sayıları: ss.124-131

Özet

Introduction. Doxorubicin and cyclophosphamide are widely used anticancer drugs with substantial toxicity in noncancerous tissue resulting from oxidative damage. Quercetin is a potent antioxidant compound. We hypothesized that quercetin administration would ameliorate the toxic effects of doxorubicin and cyclophosphamide prior to pregnancy.