Celiac Disease Prevention and Treatment


SELİMOĞLU M. A. , Karabiber H.

JOURNAL OF CLINICAL GASTROENTEROLOGY, cilt.44, ss.4-8, 2010 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 44 Konu: 1
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1097/mcg.0b013e3181b7ead2
  • Dergi Adı: JOURNAL OF CLINICAL GASTROENTEROLOGY
  • Sayfa Sayıları: ss.4-8

Özet

Celiac disease is a common multisystemic disorder that may be diagnosed at any age. Owing to the increasing prevalence, prevention strategies. including encouragement of breastfeeding and introduction of small amounts of gluten whereas still on breastfeeding at fourth to sixth month of age, become more important than before. For avoiding complications of celiac disease, a strict gluten-free diet is essential. A lifelong gluten-free diet may bring about difficulties as avoiding gluten completely is problematic owing to the contamination with gluten of presumably gluten free foods. New therapeutic approaches include enzyme supplementation, correction of the intestinal barrier defect against gluten entry, blocking of gliadin presentation by human leukocyte antigen blockers and tissue transglutaminase inhibitors.