Nanocarriers for Effective Brain Drug Delivery


Comoglu T., ARISOY S., Akkus Z. B.

CURRENT TOPICS IN MEDICINAL CHEMISTRY, cilt.17, sa.13, ss.1490-1506, 2017 (SCI-Expanded) identifier identifier

Özet

Drug delivery to the brain is an engaged research topic in the field of nanomedicine. The passage of therapeutics into the brain parenchyma is more complicated than other body tissues due to it is limited by restrict barrier structure called blood-brain barrier (BBB). Nanotechnology holds great promise to overcome the BBB and thereby enable treatment of neurodegenerative diseases. Nanocarriers have been investigated several times as effective brain drug delivery systems in the past few decades.