Yoğun Bakım Ünitelerinde İzole Edilen Acinetobacter Baumannii İzolatlarının Kolistin MİK Değerlerinin ve Direnç Genlerinin İrdelenmesi


Duman Y., Tekerekoğlu M. S.

TURKISH JOURNAL OF INTENSIVE CARE-TURK YOGUN BAKIM DERGISI, cilt.19, sa.2, ss.71-75, 2021 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.4274/tybd.galenos.2020.47965
  • Dergi Adı: TURKISH JOURNAL OF INTENSIVE CARE-TURK YOGUN BAKIM DERGISI
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.71-75
  • Anahtar Kelimeler: Acinetobacter baumannii, colistin, intensive care units, INFECTIONS
  • İnönü Üniversitesi Adresli: Evet

Özet

Objective: Acinetobacter baumannii is an opportunistic pathogen that causes healthcare-associated infections in hospitalised patients in intensive care units. A. baumannii can quickly develop resistance to antimicrobials through different mechanisms. Infections caused by multidrug-resistant (MDR) isolates have high morbidity and mortality and require long-term hospitalisation. Colistin is one of the last antimicrobials that can be used against MDR A. baumannii isolates. Due to the increase of these isolates, the use of colistin has increased worldwide. Our study aimed to investigate colistin resistance rates, minimum inhibitory concentration (MIC) values and plasmid-mediated resistance genes in isolates from the blood cultures of patients hospitalised in intensive care units.