Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Akbas S., Ozkan A. S. , Durak M. A. , Yologlu S.

NEUROCHIRURGIE, vol.67, no.6, pp.533-539, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 67 Issue: 6
  • Publication Date: 2021
  • Doi Number: 10.1016/j.neuchi.2021.04.019
  • Journal Name: NEUROCHIRURGIE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, EMBASE, MEDLINE
  • Page Numbers: pp.533-539
  • Keywords: Anesthesiology, Postoperative pain, Neurosurgery, Spine surgery, Intravenous ibuprofen, Paracetamol, DEXKETOPROFEN, ACETAMINOPHEN, MANAGEMENT, MULTICENTER, SAFETY
  • Inonu University Affiliated: Yes


Objectives. - Effective postoperative pain management after lumbar disc surgery reduces complications and improves postoperative care. The purpose of this prospective, randomized, double-blind, placebo-controlled clinical study is to evaluate the effects of IV paracetamol and ibuprofen on postoperative pain, morphine consumption and side effects of morphine in patients who underwent lumbar disc surgery.