Ischaemia-modified albumin in preeclampsia: A critical view

Gursoy A. Y., Ozdemir E. D., Ozdemir H., Candar T., Caglar G. S.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY, cilt.37, sa.3, ss.305-308, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/01443615.2016.1239070
  • Dergi Adı: JOURNAL OF OBSTETRICS AND GYNAECOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.305-308
  • Anahtar Kelimeler: Maternal, cord blood, ischaemia-modified albumin, preeclampsia, CORD BLOOD, NORMAL-PREGNANCY, SERUM-ALBUMIN, STRESS, ASSAY
  • İnönü Üniversitesi Adresli: Evet

Özet

The aim of the study was to compare ischaemia-modified albumin (IMA) levels, both original and corrected, in healthy pregnancies and pregnancies complicated with preeclampsia. Maternal and cord blood samples from study (n=16) and control (n=17) groups were collected at the time of delivery. IMA levels were given in absorbance units (ABSU). IMA levels, both original and corrected, were compared between study and control groups. No significant difference was found between maternal and cord blood IMA levels between the study and control groups [1.0 (0.3-3.5) vs 1.2 (0.2-1.4) ABSU, p=.053 and 1.0 (0.1-2.2) vs 0.9 (0.4-3.6) ABSU, p=.382, respectively]. The results were similar for maternal IMA levels, after correction of IMA levels [1.1 (0.3-5.1) vs 1.2 (0.2-1.6) ABSU, p=.292]. IMA is a novel marker for ischaemia, without precise conclusions about its value in preeclampsia. An absolute correction formula, considering all possible intervening factors, is required for more accurate results.