Trimethoprim-sulfamethoxazole treatment for meningitis owing to multidrug-resistant Elizabethkingia meningoseptica in an extremely low-birthweight, premature infant


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Gokce I. K., ONCEL M. Y., Ozdemir R., ERDEVE O., OGUZ S. S., CANPOLAT F. E., ...More

PAEDIATRICS AND INTERNATIONAL CHILD HEALTH, vol.32, no.3, pp.177-179, 2012 (SCI-Expanded) identifier identifier identifier

Abstract

Elizabethkingia meningoseptica is a recognised cause of meningitis in premature neonates and severe infections in immunocompromised adults; multi-drug resistance is a major issue. A premature infant developed sepsis, meningitis and hydrocephalus owing to E. meningoseptica and was treated successfully with trimethoprim-sulfamethoxazole (TMP-SMZ) for 3 weeks. A ventriculoperitoneal shunt was required for hydrocephalus. This is the youngest patient with meningitis caused by E. meningoseptica to have responded to TMP-SMZ.