Lutein and zeaxanthin isomers may attenuate photo-oxidative retinal damage via modulation of G protein-coupled receptors and growth factors in rats


ŞAHİN K., GENÇOĞLU H., Akdemir F. , ORHAN C., TUZCU M., ŞAHİN N., ...Daha Fazla

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, cilt.516, ss.163-170, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 516 Konu: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.bbrc.2019.06.032
  • Dergi Adı: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
  • Sayfa Sayıları: ss.163-170

Özet

Background: Retina photoreceptor cells are specially adapted for functioning over comprehensive ambient light conditions. Lutein and Zeaxanthin isomers (L/Zi) can protect photoreceptor cells against excessive light degeneration. Efficacy of L/Zi has been assessed on some G protein-coupled receptors (GPCRs), transcription and neurotrophic factors in the retina of rats exposed to incremental intense light emitting diode (LED) illumination conditions.