Lutein and zeaxanthin isomers may attenuate photo-oxidative retinal damage via modulation of G protein-coupled receptors and growth factors in rats

ŞAHİN, KAZİM; GENÇOĞLU, HASAN; Akdemir, FATİH; ORHAN, CEMAL; TUZCU, MEHMET; ŞAHİN, NURHAN; YILMAZ, İSMET; Juturu, Vijaya

doi:10.1016/j.bbrc.2019.06.032

Lutein and zeaxanthin isomers may attenuate photo-oxidative retinal damage via modulation of G protein-coupled receptors and growth factors in rats

Atıf İçin Kopyala

ŞAHİN K., GENÇOĞLU H., Akdemir F., ORHAN C., TUZCU M., ŞAHİN N., ...Daha Fazla

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, cilt.516, sa.1, ss.163-170, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 516 Sayı: 1
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.bbrc.2019.06.032
Dergi Adı: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.163-170
İnönü Üniversitesi Adresli: Evet

Özet

Background: Retina photoreceptor cells are specially adapted for functioning over comprehensive ambient light conditions. Lutein and Zeaxanthin isomers (L/Zi) can protect photoreceptor cells against excessive light degeneration. Efficacy of L/Zi has been assessed on some G protein-coupled receptors (GPCRs), transcription and neurotrophic factors in the retina of rats exposed to incremental intense light emitting diode (LED) illumination conditions.