Routine Genetic Testing for Thoracic Aortic Aneurysm and Dissection in a Clinical Setting

Ziganshin, Bulat; Bailey, Allison; Coons, Celinez; Dykas, Daniel; Charilaou, Paris; Tanriverdi, LOKMAN; Liu, Lucy; Tranquilli, Maryann; Bale, Allen; Elefteriades, John

doi:10.1016/j.athoracsur.2015.04.106

Routine Genetic Testing for Thoracic Aortic Aneurysm and Dissection in a Clinical Setting

Ziganshin B. A., Bailey A. E., Coons C., Dykas D., Charilaou P., Tanriverdi L. H., ...Daha Fazla

ANNALS OF THORACIC SURGERY, cilt.100, sa.5, ss.1604-1612, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 100 Sayı: 5
Basım Tarihi: 2015
Doi Numarası: 10.1016/j.athoracsur.2015.04.106
Dergi Adı: ANNALS OF THORACIC SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1604-1612
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
İnönü Üniversitesi Adresli: Evet

Özet

Background. Hereditary factors play an important etiologic role in thoracic aortic aneurysm and dissection (TAAD), with a number of genes proven to predispose to this condition. We initiated a clinical program for routine genetic testing of individuals for TAAD by whole exome sequencing (WES). Here we present our initial results.