Synthesis of arylacetic acid derivatives from diethyl malonate using in situ formed palladium(1,3-dialkylimidazolidin-2-ylidene) catalysts

Ozdemir I., YIGIT M., CETINKAYA E., CETINKAYA B.

TETRAHEDRON LETTERS, cilt.45, sa.30, ss.5823-5825, 2004 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 30
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/j.tetlet.2004.06.012
  • Dergi Adı: TETRAHEDRON LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.5823-5825
  • İnönü Üniversitesi Adresli: Evet

Özet

The in situ prepared three component system Pd(OAc)(2)/1,3-bis(alkyl) imidazolinium halide LHX (1-5)/Cs2CO3 catalyses the arylation of diethyl malonate efficiently with accompanying dealkoxycarbonylation. Imidazolinium salts with bulky benzyl and alkoxyethyl groups were found to be the most efficient and afforded alpha-arylacetates in high yields when employing a wide variety of substrates. (C) 2004 Elsevier Ltd. All rights reserved.