Protective effects of colchicine in an experimental model of necrotizing enterocolitis in neonatal rats

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YURTTUTAN S., Ozdemir R., CANPOLAT F. E., ONCEL M. Y., UYSAL B., UNVERDI H. G., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.183, sa.1, ss.156-162, 2013 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 183 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.jss.2013.01.002
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.156-162
  • İnönü Üniversitesi Adresli: Evet

Özet

Background: The pathophysiology of necrotizing enterocolitis (NEC) includes the massive production of endogenous cytokines with exaggerated activation of inflammatory pathways. Colchicine has been used as an anti-inflammatory agent. The aim of this study was to investigate the possible beneficial effects of colchicine in a neonatal rat model of NEC.