Protective effects of colchicine in an experimental model of necrotizing enterocolitis in neonatal rats

Creative Commons License

YURTTUTAN S., Ozdemir R., CANPOLAT F. E., ONCEL M. Y., UYSAL B., UNVERDI H. G., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.183, sa.1, ss.156-162, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 183 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.jss.2013.01.002
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.156-162
  • İnönü Üniversitesi Adresli: Evet

Özet

Background: The pathophysiology of necrotizing enterocolitis (NEC) includes the massive production of endogenous cytokines with exaggerated activation of inflammatory pathways. Colchicine has been used as an anti-inflammatory agent. The aim of this study was to investigate the possible beneficial effects of colchicine in a neonatal rat model of NEC.