Therapeutic effects of melatonin and quercetin in improvement of hepatic steatosis in rats through supression of oxidative damage

Esrefoglu M., Cetin A., Taslidere E., Elbe H., Ates B., Tok O. E., ...Daha Fazla

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.118, sa.6, ss.347-354, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 118 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4149/bll_2017_066
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.347-354
  • Anahtar Kelimeler: antioxidant, melatonin, quercetin, liver, ACID PHENETHYL ESTER, CARBON-TETRACHLORIDE, INDUCED HEPATOTOXICITY, LIPID-PEROXIDATION, LIVER-DAMAGE, CAFFEIC ACID, NONALCOHOLIC STEATOHEPATITIS, SUPEROXIDE-DISMUTASE, MECHANISMS, INJURY
  • İnönü Üniversitesi Adresli: Evet

Özet

BACKGROUND: Non-alcoholic steatohepatitis, a cause of cirrhosis, is characterized by fatty infiltration of the liver, inflammation, hepatocellular damage and fibrosis. The aim of the present study was to investigate the effects of melatonin and quercetin on CCl4-induced steatosis characterized by fatty infiltration of the liver, inflammation, hepatocellular damage and fibrosis.