Silver-N-Heterocyclic Carbene Complexes: Synthesis, Characterization, and Antimicrobial Properties

KALOGLU N., KALOĞLU M., ÖZDEMİR İ., GÜNAL S., ÖZDEMİR İ.

JOURNAL OF THE CHINESE CHEMICAL SOCIETY, cilt.64, sa.4, ss.420-426, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1002/jccs.201700024
  • Dergi Adı: JOURNAL OF THE CHINESE CHEMICAL SOCIETY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.420-426
  • Anahtar Kelimeler: N-Heterocyclic carbene, Azolium salts, Silver-N-heterocyclic carbene complexes, Antimicrobial activity, ESCHERICHIA-COLI, METAL-COMPLEXES, BENZIMIDAZOLIUM SALTS, RESPIRATORY-CHAIN, IN-VITRO, LIGANDS, IONS, NHC, ANTIBACTERIAL, BENZIMIDAZOL-2-YLIDENE
  • İnönü Üniversitesi Adresli: Evet

Özet

Six new silver complexes containing symmetrical N-heterocyclic carbene (NHC) ligands were synthesized by the reaction of azolium salts with Ag2O in CH2Cl2. These complexes were tested against Gram-negative bacterial strains (Escherichia coli and Pseudomonas aeruginosa), Grampositive bacterial strains (Enterococcus faecalis and Staphylococcus aureus), and fungal strains (Candida albicans and Candida tropicalis), and all tested complexes showed good activity against the different microorganisms.