Silver-N-Heterocyclic Carbene Complexes: Synthesis, Characterization, and Antimicrobial Properties

KALOGLU N., KALOĞLU M., ÖZDEMİR İ., GÜNAL S., ÖZDEMİR İ.

JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.64, no.4, pp.420-426, 2017 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 64 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.1002/jccs.201700024
  • Journal Name: JOURNAL OF THE CHINESE CHEMICAL SOCIETY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.420-426
  • Keywords: N-Heterocyclic carbene, Azolium salts, Silver-N-heterocyclic carbene complexes, Antimicrobial activity, ESCHERICHIA-COLI, METAL-COMPLEXES, BENZIMIDAZOLIUM SALTS, RESPIRATORY-CHAIN, IN-VITRO, LIGANDS, IONS, NHC, ANTIBACTERIAL, BENZIMIDAZOL-2-YLIDENE
  • Inonu University Affiliated: Yes

Abstract

Six new silver complexes containing symmetrical N-heterocyclic carbene (NHC) ligands were synthesized by the reaction of azolium salts with Ag2O in CH2Cl2. These complexes were tested against Gram-negative bacterial strains (Escherichia coli and Pseudomonas aeruginosa), Grampositive bacterial strains (Enterococcus faecalis and Staphylococcus aureus), and fungal strains (Candida albicans and Candida tropicalis), and all tested complexes showed good activity against the different microorganisms.