Decreased nitrate-mediated dilatation in patients with coronary artery ectasia: an ultrasonographic evaluation of brachial artery

Aksoy Y., Acikgoz N. , Sivri N., Bariskaner E., Akturk E., Turhan H., ...Daha Fazla

CORONARY ARTERY DISEASE, cilt.17, ss.365-369, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 17 Konu: 4
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1097/00019501-200606000-00007
  • Sayfa Sayıları: ss.365-369


Background Coronary artery ectasia has been defined as localized or diffuse nonobstructive lesions of the epicardial coronary arteries With a luminal dilation exceeding the 1.5-fold of normal adjacent segment or vessel diameter. Although coronary artery disease is supposed to be responsible for more than 50% of coronary ectasia, the precise pathology of coronary artery ectasia is not clearly understood. The brachial artery ultrasound test for flow-mediated endothelial-dependent vasodilatory function includes administration of sublingual nitrates to examine the vasodilating effect of an exogenous source of nitric oxide. In the present study, we aimed to compare flow-mediated and nitrate-mediated responses of brachial artery in patients with coronary artery ectasia and patients with coronary artery disease.