Impact of chromium histidinate on high fat diet induced obesity in rats

Tuzcu M., Sahin N., Orhan C., Agca C. A., Akdemir F., Tuzcu Z., ...Daha Fazla

NUTRITION & METABOLISM, cilt.8, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1186/1743-7075-8-28
  • Dergi Adı: NUTRITION & METABOLISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • İnönü Üniversitesi Adresli: Hayır

Özet

Background: Chromium (Cr) is an essential trace element that has garnered interest for use as a weight loss aid, but its molecular mechanism in obesity is not clear. In this study, an attempt has been made to investigate the effects of chromium histidinate (CrHis) on glucose transporter-2 (GLUT-2), nuclear factor erythroid 2-related factor 2 (Nrf2), heme oxygenase-1 (HO-1), nuclear factor-kappa B (NF-kappa B p65) and the oxidative stress marker 4-hydroxynonenal adducts (HNE) expressions in liver of rats fed high fat diet (HFD).