Impact of chromium histidinate on high fat diet induced obesity in rats

Tuzcu M., Sahin N., Orhan C., Agca C. A., Akdemir F., Tuzcu Z., ...More

NUTRITION & METABOLISM, vol.8, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8
  • Publication Date: 2011
  • Doi Number: 10.1186/1743-7075-8-28
  • Journal Name: NUTRITION & METABOLISM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Inonu University Affiliated: No

Abstract

Background: Chromium (Cr) is an essential trace element that has garnered interest for use as a weight loss aid, but its molecular mechanism in obesity is not clear. In this study, an attempt has been made to investigate the effects of chromium histidinate (CrHis) on glucose transporter-2 (GLUT-2), nuclear factor erythroid 2-related factor 2 (Nrf2), heme oxygenase-1 (HO-1), nuclear factor-kappa B (NF-kappa B p65) and the oxidative stress marker 4-hydroxynonenal adducts (HNE) expressions in liver of rats fed high fat diet (HFD).