Increased dilator response to nitrate and decreased flow-mediated dilatation in migraineurs

Yetkin E., Ozisik H., Ozcan C., Aksoy Y., Turhan H.

HEADACHE, cilt.47, ss.104-110, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier


Background.-It has been known that in a migraine attack intracranial and extracranial arteries on the headache side dilate and when the migraine attack has subsided, the intracranial arteries show segmental narrowing. We hypothesized that patients with migraine had an underlying systemic vasomotion abnormality and there might be an increased nitrate-mediated vasodilatory response in the brachial artery of migraineurs. Accordingly we aimed to measure endothelium dependent and independent functions of brachial artery in migraineurs and healthy subjects.