Milk thistle impedes the development of carbontetrachloride-induced liver damage in rats through suppression of bcl-2 and regulating caspase pathway

Aslan A., Can M. İ.

LIFE SCIENCES, vol.117, no.1, pp.13-18, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 117 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.1016/j.lfs.2014.09.005
  • Journal Name: LIFE SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.13-18
  • Keywords: Milk thistle, Liver damage, Caspase-3, Caspase-9, Bax, Bcl-2, SILYBUM-MARIANUM, AQUEOUS EXTRACT, ANTIOXIDANT, NRF2/HO-1, APOPTOSIS, ACID, INDUCTION, MECHANISM, SILYMARIN, SILIBININ
  • Inonu University Affiliated: No

Abstract

Aim: The objective of this study was to examine whether MT plays a protective role against the damage in the liver by administering carbontetrachloride (CCl4) to rats.