Milk thistle impedes the development of carbontetrachloride-induced liver damage in rats through suppression of bcl-2 and regulating caspase pathway

Aslan A., Can M. İ.

LIFE SCIENCES, cilt.117, sa.1, ss.13-18, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 117 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.lfs.2014.09.005
  • Dergi Adı: LIFE SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.13-18
  • Anahtar Kelimeler: Milk thistle, Liver damage, Caspase-3, Caspase-9, Bax, Bcl-2, SILYBUM-MARIANUM, AQUEOUS EXTRACT, ANTIOXIDANT, NRF2/HO-1, APOPTOSIS, ACID, INDUCTION, MECHANISM, SILYMARIN, SILIBININ
  • İnönü Üniversitesi Adresli: Hayır

Özet

Aim: The objective of this study was to examine whether MT plays a protective role against the damage in the liver by administering carbontetrachloride (CCl4) to rats.