Milk thistle impedes the development of carbontetrachloride-induced liver damage in rats through suppression of bcl-2 and regulating caspase pathway

Aslan, Abdullah; Can, MUHAMMED

doi:10.1016/j.lfs.2014.09.005

Milk thistle impedes the development of carbontetrachloride-induced liver damage in rats through suppression of bcl-2 and regulating caspase pathway

Aslan A., Can M. İ.

LIFE SCIENCES, cilt.117, sa.1, ss.13-18, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 117 Sayı: 1
Basım Tarihi: 2014
Doi Numarası: 10.1016/j.lfs.2014.09.005
Dergi Adı: LIFE SCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.13-18
Anahtar Kelimeler: Milk thistle, Liver damage, Caspase-3, Caspase-9, Bax, Bcl-2, SILYBUM-MARIANUM, AQUEOUS EXTRACT, ANTIOXIDANT, NRF2/HO-1, APOPTOSIS, ACID, INDUCTION, MECHANISM, SILYMARIN, SILIBININ
İnönü Üniversitesi Adresli: Hayır

Özet

Aim: The objective of this study was to examine whether MT plays a protective role against the damage in the liver by administering carbontetrachloride (CCl4) to rats.