Comparison of the Predictive Roles of Risk Scores of In-Hospital Major Adverse Cardiovascular Events in Patients with Non-ST Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention

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Akturk E., Askin L., Tasolar H., Turkmen S., Kaya H.

MEDICAL PRINCIPLES AND PRACTICE, vol.27, no.5, pp.459-465, 2018 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 27 Issue: 5
  • Publication Date: 2018
  • Doi Number: 10.1159/000489399
  • Journal Name: MEDICAL PRINCIPLES AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.459-465
  • Keywords: Risk scores, Cardiovascular events, Non-ST elevation myocardial infarction, LONG-TERM MORTALITY, SYNTAX SCORE, LEFT MAIN, ARTERY-DISEASE, CLINICAL-OUTCOMES, DECISION-MAKING, GLOBAL REGISTRY, CARDIAC-SURGERY, ELUTING STENT, REVASCULARIZATION
  • Inonu University Affiliated: No

Abstract

Objective: We evaluated the relationship between various risk scores (SYNTAX score [SS], SYNTAX score-II [SS-II], thrombolysis in myocardial infarction [TIMI] risk scores, and Global Registry of Acute Coronary Events [GRACE] risk scores) and major adverse cardiovascular events (MACE) in non-ST elevation myocardial infarction (NSTEMI) patients undergoing percutaneous coronary intervention (PCI). Subjects and Methods: The study population were selected from among 589 patients who underwent coronary angiography with a diagnosis of NSTEMI. TIMI and GRACE risk scores were calculated. SS and SS-II were calculated in all patients, and points were added according to the predefined algorithm, taking into account the other 6 clinical variables being monitored (age, sex, left ventricular ejection fraction, creatinine clearance, chronic obstructive pulmonary disease, and peripheral artery disease). Patients were classified into tertile 1 (SS < 22), tertile 2 (SS 23-32), and tertile 3 (SS > 32). Results: The group with high SS-II for PCI values in the risk scores were observed from tertile 1 to tertile 3 (from 25.0 +/- 7.7 to 31.6 +/- 9.4, p < 0.001, respectively). The SS-II score in patients with PCI was an independent predictor of MACE, in-hospital mortality, nonfatal myocardial infarction, and stent thrombosis (OR 1.082, 95% CI 1.036-1.131, p < 0.001). The overall MACE, in-hospital mortality, and nonfatal myocardial infarction rates were significantly higher in the high SS-II for PCI group (p < 0.001). Conclusion: TIMI and GRACE risk scores were able to predict MACE. In addition to these, SS-II was also able to predict in-hospital mortality, nonfatal myocardial infarction, and stent thrombosis. (c) 2018 The Author(s) Published by S. Karger AG, Basel